Accelerate antibody discovery with HDX-MS epitope and paratope mapping.
HDX-MS epitope and paratope mapping to characterize antibody–antigen interactions and support therapeutic antibody development.
Why RaptMAb
Scientific Expertise
Over a decade of hands-on HDX-MS experience supporting antibody characterization and therapeutic development.
Collaborative Partnership
Work directly with experienced scientists from study design and experimental execution through data interpretation.
Tailored Experimental Design
Every study is designed around your biological question, sample characteristics, and development objectives.
Actionable Insights
Receive comprehensive data analysis and scientifically rigorous reports to support confident decision-making.
Direct Access to Our Scientists
Communicate directly with the scientists performing your study for efficient collaboration and expert guidance.
Flexible for Academic & Industry Needs
Project scope and scientific support tailored to the needs of academic laboratories, biotechnology companies, and pharmaceutical organizations.
Explore Our Services
Unlock structural insights with Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS). From antibody characterization to protein interactions and conformational dynamics, RaptMAb delivers scientifically rigorous studies to support drug discovery and development.
Our Workflow
Every project begins with your scientific question. We work collaboratively to design an HDX-MS study that delivers meaningful insights aligned with your research objectives.
- 01
Consultation
We begin by discussing your research goals, available samples, and key questions. This allows us to understand what you need to learn—not just what experiment to perform.
- 02
Study Design
Based on your objectives, we design an HDX-MS study with appropriate controls, experimental conditions, and analytical approaches to maximize the value of the data.
- 03
HDX-MS Analysis
Our scientists perform the HDX-MS experiments and analyze the data to characterize biomolecular interactions, binding interfaces, and conformational dynamics.
- 04
Scientific Interpretation
Results are interpreted in the context of your biological question and delivered in a comprehensive report with structural visualizations and scientific discussion.
Applications
Supporting critical decisions across therapeutic discovery and structural biology.
Antibody Discovery
Identify epitopes and paratopes to support lead selection, affinity maturation, and antibody engineering.
Mechanism of Action
Understand how therapeutic molecules interact with their targets and reveal functional binding interfaces.
Biosimilar Characterization
Compare higher-order structure and binding behavior to support biosimilar development and comparability studies.
Small-Molecule Drug Discovery
Characterize protein–ligand interactions and investigate binding sites to support lead optimization.
Protein Structural Biology
Investigate conformational dynamics and structural changes associated with protein function, stability, and regulation.
Protein Engineering
Evaluate the structural impact of mutations and rational protein design strategies.
Ready to advance your research?
Schedule a consultation for your project.
Tell us about your system, scientific question, and timeline. We'll follow up with a scope and quote.
Prefer email? info@raptmab.com
Frequently asked questions
What is RaptMAb?
RaptMAb Biotechnology provides HDX-MS epitope and paratope mapping, protein interaction analysis, and structural characterization for biotech, pharma, and academic teams.
What is HDX-MS epitope and paratope mapping?
HDX-MS stands for Hydrogen–Deuterium Exchange Mass Spectrometry. HDX-MS epitope and paratope mapping characterizes antibody–antigen interactions, giving detailed structural insights into how therapeutic antibodies recognize and interact with their targets. HDX-MS provides solution-phase structural information that complements traditional biochemical and biophysical techniques.
Who is RaptMAb for?
Academic laboratories, biotechnology companies, and pharmaceutical organizations. Project scope and scientific support are tailored to the needs of each.
What services does RaptMAb offer?
HDX-MS services for antibody characterization, protein interaction analysis, and protein structural characterization. Applications include antibody discovery, mechanism of action, biosimilar characterization, small-molecule drug discovery, protein structural biology, and protein engineering.
What does a project include, and how does it start?
Every project begins with your scientific question. We start with a consultation about your research goals, available samples, and key questions, then design the HDX-MS study, perform the experiments, analyze the data, and interpret the results. You communicate directly with the scientists performing your study, and results are delivered in a comprehensive report with structural visualizations and scientific discussion.
How do I request a scope and quote?
Schedule a consultation using the contact form on this page, or email info@raptmab.com. Tell us about your system, scientific question, and timeline, and we'll follow up with a scope and quote.